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Check-in
22Jan2026Select date
Check-out
23Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Details

201 North Main Street, Hannibal, Missouri, United States, 63401
-
Steps from Bluff City Theater
Perfect
9.0
/10
4.6
/5

Main Street Bed & Breakfast - A historic downtown property with river views and cultural attractions nearby

Located at the corner of Center and Main Streets in historic downtown Hannibal, this 3-star Hannibal hotel offers suites with private entrances, river views, and spa baths. Main Street Bed & Breakfast provides soundproofed rooms equipped with flat-screen TVs, Bluetooth-enabled clock radios, and complimentary WiFi. Each suite features a seating area, tea/coffee facilities with Columbian coffee options, and a mini-fridge. A continental breakfast is served daily, with a dedicated breakfast seating area. The property includes barbecue facilities and a hot tub for guest use. Cultural attractions within 0.3-0.5 miles include the Haunted House on Hill Street Wax Museum, Molly Brown Birthplace, and Jim's Journey: The Huck Finn Freedom Center. The Mark Twain Boyhood Home and Museum stands 0.3 miles away, while Quincy Regional Airport is located 18 miles from the property.

Pros

Eight restaurants and cafes, including Java Jive and Due Amici Pizzeria, within 0.3 miles

Self check-in available after 8 PM

Free parking available from 8 AM to 8 PM

Private entrances for all suites

Cons

Check-in ends at 8 PM for standard check-in

Airport is 18 miles away

“This historic bed and breakfast, housed in a former bank, provides a distinctive stay in Hannibal's downtown. I particularly appreciate the personalized touch, with local historians ready to engage guests. Homemade treats and proximity to the Mississippi River make it a comfortable and convenient base for exploring the area's attractions.”
Hotel logo
Charlotte EvansHead of Editorial at Hotelsdowntown
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Select room type

Choose from double rooms, family suites, and premium stays. Enjoy breakfast, flexible cancellations, and exclusive deals.
Deluxe Queen Suite
2 persons
400 sq. feet 
1 King-size bed
Shower
Coffee machine
Deluxe King Suite
2 persons
445 sq. feet 
1 King-size bed
Shower
Coffee machine

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Facilities

Hotel has comfortable rooms, premium services, and a prime downtown location

General

  • No smoking on site
  • Free Wi-Fi
  • Free parking
  • VIP check-in/ -out
  • Express check-in/ -out
  • Concierge desk
  • No pets allowed
  • Security
  • Adults only
  • Smoke detectors
  • Fire extinguishers
  • Key access

Sports & Fitness

  • Canoeing
  • Hiking
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Valet parking
  • Housekeeping
  • Tours/Ticket assistance

Dining

  • In-room breakfast
  • Special diet menus

Spa & Leisure

  • Aqua park
  • Live entertainment
  • Night club
  • BBQ facilities
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

201 North Main Street, Hannibal, Missouri, United States, 63401
Map view
201 North Main Street, Hannibal, Missouri, United States, 63401
Nearby
Museum
Mark Twain Boyhood Home and Museum
1400 ft
Bridge
Mark Twain Memorial Lighthouse
1400 ft
Hannibal
Tom and Huck's Statue
1400 ft
Museum
Jim's Journey
1400 ft
211 Hill St
Haunted House on Hill Street Wax Museum
800 ft
Hannibal
Becky Thatcher's House
1400 ft
114 S 3rd St
Karlocks Kars and Pop Culture Museum
1100 ft
320 N 3rd St
Big River Train Town
1400 ft
600 Butler St
Molly Brown Museum and Home
1400 ft
Library
Hannibal Free Public Library
1800 ft
Park
Glascock's Landing
1400 ft
162-198 North St
Tom Sawyer and Huck Finn Statue
1100 ft
320 Broadway
Hannibal Parks & Recreation
1100 ft
Museum
Hannibal History Museum
1400 ft
600 Butler St
Molly Brown Birthplace
1400 ft
Store
Bluff City Theatre
1400 ft
Restaurants
The Brick Oven
100 ft
207 Center Street
Java Jive
200 ft
211 N Main St
Finn's Food and Spirits
200 ft
214 N Main St
Chocolaterie Stam
300 ft
103 N Main St
Riverside Restaurant
600 ft
111 Bird St
Mark Twain Dinette
1100 ft
400 N 3rd St
Explore Hannibal
Local Experiences
Top Attractions
Activities
Dining
Entertainment
Mark Twain Boyhood Home and Museum
5 minutes' walk
This museum showcases Twain's early life, featuring guided tours and insightful exhibits about his iconic works.
Haunted House on Hill Street Wax Museum
3 minutes' walk
A spooky attraction with detailed wax figures depicting famous ghosts, perfect for a fun family outing.
Lovers Leap
19 minutes' walk
A scenic overlook offering stunning river views, ideal for sunset watching or a romantic picnic.
Riverview Park
25 minutes' walk
A serene park by the river with trails, playgrounds, and picnic areas, great for relaxation and outdoor activities.
Hiking at Saddle Cliffs
5 minutes' drive
Adventure seekers can hike rugged trails with breathtaking views. Parking is available at the trailhead.
Relaxation at Huckleberry Park
35 minutes' walk
This peaceful park includes walking paths and benches, perfect for unwinding amid nature.
The Brick Oven
1 minute' walk
A cozy spot known for its delicious pizzas and hearty pasta, with a friendly atmosphere. Reservations are recommended.
Finn's Food and Spirits
1 minute' walk
Casual dining with American classics and craft beers. Popular for its vibrant ambiance and tasty burgers.
Riverside Restaurant
2 minutes' walk
Enjoy river views with a menu of fresh seafood and local dishes. Vegetarians will find great options, too.
Stagecoach Theatre
5 minutes' drive
A local theater offering comedy shows and musicals. Check for family-friendly performances throughout the week.
Java Jive
1 minute' walk
A charming coffee shop with live music on weekends, perfect for enjoying great brews in a lively atmosphere.
Getting around
City Centre
Hannibal5 min  ·  1400 ft
Airports
Quincy Regional Airport (UIN)68 min  ·  27.8 mi
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Property information and rules
Check-in
from 14:00-20:00
Check-out
from 06:00-11:00
Guest Parking
Private parking is possible on site for free.
Internet
is available in for free.
Breakfast
At the hotel Main Street Bed & Breakfast guests are invited to a full breakfast served for free. 
Pets
Pets are not allowed.
FAQs
About Main Street Bed & Breakfast
What are the check-in and check-out times for Main Street Bed & Breakfast?
Check-in is from 14:00 and check-out is by 11:00.
Is parking available at Main Street Bed & Breakfast?
Free private parking is available on-site, and no reservation is needed.
How far is Main Street Bed & Breakfast from Quincy Regional Airport?
The hotel is located 44 km from Quincy Regional Airport.
What type of breakfast is offered at Main Street Bed & Breakfast?
Guests can enjoy a continental breakfast, which includes fruit juices, muffins, and fresh fruits.
What amenities are available in the rooms at Main Street Bed & Breakfast?
Rooms are equipped with air conditioning, a flat-screen TV, a coffee machine, a fridge, and a spa bath.
What nearby attractions are accessible from Main Street Bed & Breakfast?
Nearby attractions include Mark Twain Boyhood Home and Museum (0.5 km), Bluff City Theater (0.5 km), and Jim's Journey (0.5 km).
What recreational activities can guests enjoy at Main Street Bed & Breakfast?
Guests can engage in activities such as cycling, fishing, and hiking in the surrounding area.
Are there any restaurants near Main Street Bed & Breakfast?
Nearby dining options include Rumor Has IT, Java Jive, and Finn's Food and Spirits, all within 0.5 km.
What unique features does Main Street Bed & Breakfast have?
The hotel is located in a historic building and offers a hot tub and personalized guest interactions with local historians.
What languages are spoken by the staff at Main Street Bed & Breakfast?
The staff primarily speaks English.
Does Main Street Bed & Breakfast have a barbecue facility?
Yes, the hotel provides barbecue facilities for guests.

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