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From164US$ /night
Check-in
02Jun2025Select date
Check-out
03Jun2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Details

700 W Main Street, Louisville, Kentucky, United States of America, 40202

21C Museum Hotel Louisville - Contemporary Art Museum Hotel with Bourbon-Inspired Dining and Downtown Cultural Access

Located in historic Whiskey Row, this 5-star Louisville hotel merges a 9000-square-foot contemporary art museum with a 91-room boutique property. 21C Museum Hotel features the acclaimed Proof on Main restaurant, specializing in Ohio River Valley cuisine under Executive Chef Cody Stone. Guest rooms, housed in former bourbon and tobacco warehouses, include premium Bryte Restorative Sleep Beds, flat-screen TVs, minibars, and coffee makers, with some rooms offering Ohio River views. Four private galleries accommodate meetings and events for 10 to 60 guests. The property hosts regular art exhibitions, installations, and cultural events including the Fork & Bottle dinner series featuring regional distillers. 21c Museum Hotel Louisville stands within a half-mile radius of the Kentucky Museum of Art & Craft, Frazier International History Museum, and Muhammad Ali Center. The free ZeroBus, accessible two roads from the hotel, connects guests to downtown attractions like Slugger Field and Waterfront Park.

21C Museum Hotel Louisville: Pros

- Regular cultural programming includes guest distiller events and art performances - Historic warehouse architecture preserved throughout the property - Dedicated event staff provides customized catering menus - On-site contemporary art museum with rotating exhibitions

21C Museum Hotel Louisville: Cons

- Downtown location can be busy during major events and festivals - Some rooms face busy city streets

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Select room type

Choose from double rooms, family suites, and premium stays. Enjoy breakfast, flexible cancellations, and exclusive deals.
King Room
Max:
2 persons
315 sq. feet 
Bed options:
1 King Size Bed
City view
Shower
Coffee machine
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Deluxe King Room
Max:
3 persons
335 sq. feet 
Bed options:
1 King Size Bed
Shower
Coffee machine
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Corner Suite
Max:
2 persons
660 sq. feet 
Bed options:
1 King Size Bed
City view
Shower
Coffee machine
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Getting around

Discover available transportation options for smooth travel around the city

City Center
Louisville 1.2 mi
Airports
Louisville (SDF) 7.4 mi

Facilities

Hotel has comfortable rooms, premium services, and a prime downtown location

General

  • No smoking on site
  • Wi-Fi
  • No parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Baggage storage
  • Locker room
  • Allergy-free rooms
  • Elevator
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness center
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business center
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cribs

Spa & Leisure

  • Spa & wellness center
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
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Location

700 W Main Street, Louisville, Kentucky, United States of America, 40202
Map view
700 W Main Street, Louisville, Kentucky, United States of America, 40202
Nearby
Museums
Louisville Slugger Museum & Bat Factory
600 ft
Museums
Muhammad Ali Center
1000 ft
Museums
Kentucky Science Center
500 ft
Museums
The Frazier History Museum
900 ft
Museums
Kentucky Museum of Art and Craft
300 ft
528 W Main St
Evan Williams Bourbon Experience
700 ft
Gallery
Flame Run Glass Studio and Gallery
1000 ft
500 W Main St
The Belvedere
900 ft
Night club
Jimmy Can't Dance
300 ft
801 W Main St
Michter's Fort Nelson Distillery
500 ft
Libraries
Sons of the American Revolution Genealogical Research Library
700 ft
120 N 10th St
Kentucky Peerless Distilling Co
1600 ft
401 W River Rd
Belle of Louisville Riverboats
2000 ft
Restaurants
Proof On Main
100 ft
702 West Main Street
Mussel & Burger Bar Downtown
200 ft
113 S 7th St Located in Louisville's Central Business District
Bristol Bar & Grille
400 ft
614 W Main St
Atlantic No. 5
600 ft
605 W Main St Located in Louisville's Central Business District.
Los Aztecas Mexican Restaurant
600 ft
445 E Market St
Vincenzo's Italian Restaurant
1500 ft
150 S 5th St
Jockey Silks Bourbon Bar
1600 ft
140 N 4th St 2nd Floor - West Tower
Dish on Market
1600 ft
434 W Market St
Quiznos
1800 ft
223 S 5th St
Swizzle Dinner & Drinks
1800 ft
140 N Fourth St 25th Floor
Cafe Magnolia
2000 ft
140 N 4th St Galt House Hotel
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Check-in
02Jun2025Select date
Check-out
03Jun2025Select date
Rooms and Guests2 Guests, 1 Room