Downtown hotels in Rochester, United States - page 2

Carefully selected hotels offering comfort and convenience in Rochester, United States
Check-in
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Check-out
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Rooms and Guests2 Guests, 1 Room
Rochester offers attractions like the George Eastman Museum, the Strong National Museum of Play, and the beautiful Highland Park. You can also enjoy outdoor fun at Seneca Park and take a gamble at the Del Lago Resort & Casino. For hotels close to Mayo Clinic or pet-friendly options, you'll find many choices that cater to your needs. The listings here feature carefully selected hotels known for their excellent amenities and guest reviews. To get the best rates, consider booking in advance, especially during festivals. Public transport like buses and rideshares make getting around easy.
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21-27 out of 27
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7.0
Very good
MapNear Mayo Clinic1.3km
  • Indoor pool with water slides
  • On-site dining options available
  • Complimentary shuttle service provided
  • Indoor Pool
  • Fitness Centre
  • Spa Jacuzzi
Family-friendly hotel with recreational amenities and dining
FromUS$ 69 /nightSelect
MapClose to Mayo Clinic200m
  • Rooftop terrace with city views
  • Two onsite restaurants available
  • Located near Mayo Clinic
  • Indoor pool
  • Fitness center
  • Executive lounge
Hotel with rooftop views and premium dining options
FromUS$ 265 /nightSelect
9.0
Perfect
MapAdjacent to Mayo Clinic0m
  • Indoor pool and fitness center
  • On-site restaurant with diverse menu
  • Direct access to Mayo Clinic
  • Indoor Pool
  • On-site Dining
  • Fitness Center
Hotel connected to top-rated healthcare and amenities
FromUS$ 109 /nightSelect
MapDirect access to Mayo Clinic350m
  • Complimentary evening social hour
  • Functional kitchen in every room
  • Accessible direct walk to Mayo Clinic
  • Fitness center
  • Rooftop patio
  • Business center
Hotel offering extended stay suites near Mayo Clinic
FromUS$ 164 /nightSelect
MapAcross from Saint Marys Hospital0m
  • Indoor pool with whirlpool
  • On-site dining with Starbucks
  • Free shuttle to Mayo Clinic
  • Indoor Pool
  • Fitness Center
  • On-site Restaurant
Hotel with convenient access to medical facilities and dining
FromUS$ 137 /nightSelect
MapNear Mayo Clinic200m
  • Indoor pool with kiddie area
  • Award-winning Twigs Tavern restaurant
  • On-call shuttle to Mayo Clinic
  • Indoor pool
  • Fitness center
  • Game room
Hotel offering tailored services for Mayo Clinic visitors
FromUS$ 93 /nightSelect
MapProximity to Mayo Clinic400m
  • Free shuttle service to Mayo Clinic campuses
  • Fully equipped kitchens in all rooms
  • On-site coffee shop with craft beverages
  • Fitness Center
  • Coffee Shop
  • Business Center
Hotel offering extended stay with kitchen amenities and fitness center
FromUS$ 194 /nightSelect
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Check-in
22Jan2026Select date
Check-out
23Jan2026Select date
Rooms and Guests2 Guests, 1 Room