TWENTYONE HOTEL ROME | Rome ★ Prime Downtown Location & Comfort

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Hotel Details

Via Cola Di Rienzo 23, Rome, Italy, 00192

Twentyone Hotel - A modern boutique hotel between Vatican City and Spanish Steps with panoramic terrace views

Located in Rome's upscale Prati district, this 4-star Rome hotel features 93 rooms with custom designer furniture and modern amenities. The property sits halfway between St. Peter's Basilica and Piazza di Spagna, placing guests a 15-minute walk from Vatican City. Each accommodation includes LCD TVs with satellite channels, minibars, air conditioning, and complimentary WiFi. The Deluxe rooms on the fifth floor offer private terraces overlooking St. Peter's Dome and city monuments. Bistrò 21 serves traditional Roman and Italian cuisine with daily rotating specialties like Monday gnocchi and Friday fish dishes. Twentyone Hotel stands just 0.3 miles from Lepanto metro station and 2 miles from Roma Termini railway station. The property provides direct access to Villa Borghese gardens and places guests within walking distance of the Spanish Steps, Trevi Fountain, and Vatican Museums.

Twentyone Hotel: Pros

- Fifth-floor terrace rooms provide unobstructed views of St. Peter's Dome and Rome's skyline - Junior Suites feature spa baths and round beds - Daily rotating authentic Italian menu at the on-site restaurant - Strategic location between major landmarks with metro access

Twentyone Hotel: Cons

- 2 miles distance from Roma Termini station requires transit planning - Popular tourist area can become crowded during peak seasons

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Select room type

Choose from double rooms, family suites, and premium stays. Enjoy breakfast, flexible cancellations, and exclusive deals.

Twin Room

Max:

2 persons

195 sq. feet

Bed options:

2 Single beds

Shower

Heating

room details

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Triple Room

Max:

3 persons

240 sq. feet

Bed options:

3 Single beds

Shower

Heating

room details

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Double Room

Max:

2 persons

195 sq. feet

Bed options:

1 King Size Bed

Shower

Heating

room details

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Getting around

Discover available transportation options for smooth travel around the city

City Center

Rome 1.4 mi

Airports

Ciampino (CIA) 11.6 mi

Fiumicino (FCO) 18.4 mi

Train

Roma San Pietro Train Station 1.2 mi

Metro stations

Lepanto Metro Station1400 ft

Facilities

Hotel has comfortable rooms, premium services, and a prime downtown location

Delicious Breakfast Spread

“I thoroughly enjoyed the breakfast at Twentyone Hotel. The options were fresh and varied, including delicious pastries and typical Italian offerings. It was a great way to start my day before heading out to explore Rome!” view full review

Modern and Comfortable Room

“The double room I stayed in was of good standard with modern decor. It had all the essential amenities, including a good air conditioning unit and a safe for my valuables, which made my stay comfortable and stress-free.” view full review

Clean and Contemporary Bathroom

“I found the bathroom to be clean and modern with ample towels provided. Although it was a bit small, it met my needs perfectly and had a sleek design that added to the overall contemporary feel of the room.” view full review

Cozy and Inviting Atmosphere

“The bedroom had a stylish design and was a cozy retreat after a day of exploring. The bed was comfortable, and the decor created a cute atmosphere that enhanced my overall experience at the hotel.” view full review

General

Non-smoking rooms
Wi-Fi
Parking
Safe deposit box
24-hour reception
Express check-in/ -out
No pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Security
Baggage storage
Allergy-free rooms
Elevator
Barber shop
Coffee shop
Smoke detectors
Electric vehicle charging station
Fire extinguishers
Key card access

Sports & Fitness

Fitness center

Services

Paid airport shuttle
Room service
Housekeeping
Laundry
Dry cleaning
Tours/Ticket assistance
Welcome drink

Dining

In-room breakfast
Restaurant
Snack bar
Bar/ Lounge area
Packed lunches
Special diet menus

Business

Fax/Photocopying

Children

Cribs
Children's buffet

Facilities for people with disabilities

Toilet for disabled
Bathroom for disabled

Spa & Leisure

Garden area
Leisure/ TV room

Room features

Air conditioning
Heating
Mini-bar
Soundproofed rooms
Sitting area
Terrace
Garden furniture
Tea and coffee facilities
Ironing facilities

Bathroom

Free toiletries
Sink

Media

Flat-screen TV
AM/FM alarm clock

Room decor

Carpeted floor

Location

Via Cola Di Rienzo 23, Rome, Italy, 00192

Map view

street view

Via Cola Di Rienzo 23, Rome, Italy, 00192

City landmarks

Fountains

Trevi Fountain

1.1 mi

Church

Pantheon

5200 ft

Square

The Colosseum

1.8 mi

Landmark

Piazza Navona

4400 ft

Museums

Vatican Museums

1.0 mi

Church

St. Peter's Basilica

1.1 mi

Square

Saint Peter's Square

4900 ft

Largo della Salara Vecchia

Roman Forum

1.5 mi

Piazza di Spagna

4500 ft

Square

Spanish Steps

5000 ft

Bridges

St. Angelo Bridge

3500 ft

Square

Piazza del Popolo

2500 ft

Square

Piazza Venezia

1.3 mi

Church

Sistine Chapel

1.1 mi

Cemetery

Altar of the Fatherland

1.4 mi

Square

Campo de' Fiori

1.1 mi

Piazza San Pietro

Vatican City

1.1 mi

Museums

Borghese Gallery and Museum

1.2 mi

Bridges

St. Angelo Bridge

3600 ft

Vatikanstadt 00120 Città del Vaticano VA

Torre di San Giovanni

1.6 mi

Church

Church of Saint Louis the French

4500 ft

Square

Largo di Torre Argentina

1.1 mi

Church

Church of Santa Maria del Popolo

2300 ft

Zoo

Bioparco di Roma

1.3 mi

Church

Santa Maria in Trastevere

1.4 mi

Museums

Capitoline Museums

1.3 mi

Square

Piazza Barberini

1.1 mi

Museums

Museum of the Ara Pacis

3000 ft

Square

Pincian Hill

3200 ft

Church

Church of the Gesu

1.2 mi

Nearby

Bridges

St. Angelo Bridge

3500 ft

Square

Piazza del Popolo

2500 ft

Bridges

St. Angelo Bridge

3600 ft

Church

Church of Santa Maria del Popolo

2300 ft

Church

Basilica of Sant' Agostino

3400 ft

Restaurants

Bistro' 21

100 ft

Via Cola di Rienzo 23 Hotel Twenty One

Cantieri Bistrot

300 ft

Via Cola di Rienzo 16

Le Sicilianedde

300 ft

Via Cola di Rienzo

La Pinseria Prati

300 ft

Via Lucrezio Caro 60

Pasticceria Sanzini

500 ft

Via Valadier

Ristorante Grekos Taste the Myth

700 ft

Via Dei Gracchi 282 Incrocio via Marcantonio Colonna

Ruyi

800 ft

Via Valadier 14

Quelli del bar Cicerone

600 ft

Via Cicerone 68

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TWENTYONE HOTEL ROME, Rome

Hotel Details

Twentyone Hotel - A modern boutique hotel between Vatican City and Spanish Steps with panoramic terrace views

Twentyone Hotel: Pros

Twentyone Hotel: Cons

Select room type

Check Availability & Prices

Getting around

Facilities

General

Sports & Fitness

Services

Dining

Business

Children

Facilities for people with disabilities

Spa & Leisure

Room features

Bathroom

Media

Room decor

Location

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